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Propulsion par l'actine : Génération de force

Abstract : This thesis has the aim of studying the mechanisms of production of forces induced by the polymerization of actin within the cell. These mechanisms intervene in particular at the time of the displacement and the division of cells. All these activities require deformation of the cell so that it acquires a "polarity". Under the plasma membrane is the "cytoskeleton", an essential structure that maintains the shape of the cell. Actin, the principal component of this system, is a biopolymer that exist in filament and monomer form. Actin filaments are organized into a three-dimensional structure, adapted to the mechanical functions needed by the cell. We analyzed how the growth of an actin gel led to a polarity and to the movement. Then using a biomimetic system, we characterized and described the constraints exerted by the actin gel for the propulsion.
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Contributor : Hakim Boukellal <>
Submitted on : Monday, June 6, 2005 - 10:59:18 AM
Last modification on : Thursday, December 10, 2020 - 10:52:44 AM
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  • HAL Id : tel-00009387, version 1


Hakim Boukellal. Propulsion par l'actine : Génération de force. Sciences du Vivant [q-bio]. Université Pierre et Marie Curie - Paris VI, 2004. Français. ⟨tel-00009387⟩



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