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Modulation de la production de cytokines par l'environnement

Elodie Merlot 
Abstract : The immune consequences of environmental stress are complex and difficult to predict. Stress affects the immune system either at the level of innate immunity, through the alteration
of inflammatory reactivity, or at the level of acquired immunity, through the modulation of Th1 and Th2 cytokines. In social species, social environment contributes to the development
and expression of diseases. The social position in a group modulates susceptibility to infections. However, the endocrine and immune mechanisms involved in these differences are
not known. Instability in the social organization generates a severe stress of which immune consequences are still controversial.
The purposes of this thesis are (1) to describe the influence of social status on the endocrine and immune systems, (2) to specify the effects of social stress on cytokine production and susceptibility to infections and (3) to look for possible sources of variability in the immune consequences of social stress
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Submitted on : Tuesday, November 30, 2004 - 4:26:50 PM
Last modification on : Thursday, March 18, 2021 - 12:56:03 PM
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  • HAL Id : tel-00007518, version 1


Elodie Merlot. Modulation de la production de cytokines par l'environnement. Immunologie. Institut national agronomique paris-grignon - INA P-G, 2003. Français. ⟨tel-00007518⟩



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