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Métabolites secondaires des plantes et comportement animal: surveillance sanitaire et observations de l'alimentation des chimpanzés (Pan troglodytes schweinfurthii) en Ouganda. Activités biologiques et étude chimique de plantes consommées

Abstract : In order to select plants with pharmacological effects, behavioural and health monitoring of wild chimpanzees (Pan troglodytes schweinfurthii), from Kibale National Park, in Uganda, has been conducted. Fecal and urine samples ((252 and 76) were analyzed and the health status evaluated. 84 crude extracts from 24 plants species from chimpanzees' diet were tested in vitro for a wide range of biological properties such as antimalarial, anthelminthic, antileishmanial, antimicrobial, cytotoxic activities and effects on the feeding behavior. Chemical investigations led to the isolation of bioactive compounds from plants namely Uvariopsis congensis (acetogenins), Diospyros abyssinica (binaphtoquinones) and Trichilia rubescens (two new limonoids).These results are consistent with the hypothesis that certain plants may have prophylactic and/or therapeutic effects on the health of chimpanzees. In addition to shedding light on the complex interaction between plants, animals and pathogens, the study of self-medication in great apes is expected to provide a novel approach to the discovery of new bioactive products
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https://tel.archives-ouvertes.fr/tel-00006170
Contributor : Sabrina Krief <>
Submitted on : Saturday, May 29, 2004 - 6:29:47 AM
Last modification on : Wednesday, October 14, 2020 - 3:41:13 AM
Long-term archiving on: : Wednesday, September 12, 2012 - 4:05:11 PM

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  • HAL Id : tel-00006170, version 1

Citation

Sabrina Krief. Métabolites secondaires des plantes et comportement animal: surveillance sanitaire et observations de l'alimentation des chimpanzés (Pan troglodytes schweinfurthii) en Ouganda. Activités biologiques et étude chimique de plantes consommées. Sciences du Vivant [q-bio]. Museum national d'histoire naturelle - MNHN PARIS, 2003. Français. ⟨tel-00006170⟩

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