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Role of the basal ganglia in conditional associative learning : a multidisciplinary approach

Abstract : The arbitrary mapping of sensory information onto action forms an important element of the intelligent behavior of primates (also called conditional associative learning). The cortico-basal ganglia-thalamo-cortical loops are thought to play a key role in such behavior. The present research was undertaken to investigate the role of the basal ganglia (BG) in conditional visuo-motor associative learning using three complementary approaches: 1) single-unit recordings in awake monkeys, 2) behavioral testing in patients suffering from Parkinson's disease (a neurodegenerative disease affecting the BG), and 3) functional neuroimaging in healthy subjects. The results of all three studies converge to indicate that the BG are involved in both the acquisition and the retention phases of visuo-motor associations.
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https://tel.archives-ouvertes.fr/tel-00006160
Contributor : Fadila Hadj-Bouziane <>
Submitted on : Thursday, May 27, 2004 - 6:31:32 PM
Last modification on : Thursday, November 19, 2020 - 8:30:04 AM
Long-term archiving on: : Friday, April 2, 2010 - 8:00:27 PM

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  • HAL Id : tel-00006160, version 1

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Fadila Hadj-Bouziane. Role of the basal ganglia in conditional associative learning : a multidisciplinary approach. Neurons and Cognition [q-bio.NC]. Université Claude Bernard - Lyon I, 2003. English. ⟨tel-00006160⟩

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