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Contribution à l'histoire de la recherche médicale : autour des travaux de Jean Bernard et de ses collaborateurs sur la leucémie aiguë, 1940-1970

Abstract : This thesis explores part of the process of the emergence of biomedicine by focussing on Jean Bernard and his associates' work on acute leukaemia (Paris, 1940-1970). It examines the search process for treatments and biological explanations in the face of the changes of medical research over that period. It shows how some cures were achieved thanks to the combination of chemotherapeutic agents, whereas exchange transfusions and bone marrow transplantation led only to remissions. It also analyses more basic investigations relating mainly to the cytological, the virological and the immunological characteristics of human and animal leukaemias. These developments were shaped by the molecularization of biology and medicine, by the standardization of materials and methods, by more collaborative work with both industrial and academic groups, especially American, as well as by a raise in public and charity funding, which ended in the creation of new institutions.
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https://tel.archives-ouvertes.fr/tel-00004194
Contributor : Christelle Rigal <>
Submitted on : Friday, January 16, 2004 - 2:27:27 PM
Last modification on : Friday, April 10, 2020 - 6:02:01 PM
Long-term archiving on: : Friday, April 2, 2010 - 7:24:10 PM

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  • HAL Id : tel-00004194, version 1

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Christelle Rigal. Contribution à l'histoire de la recherche médicale : autour des travaux de Jean Bernard et de ses collaborateurs sur la leucémie aiguë, 1940-1970. Philosophie. Université Paris-Diderot - Paris VII, 2003. Français. ⟨tel-00004194⟩

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