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Caractérisation Biomécanique et Modélisation 3D par Imagerie X et IRM haute résolution de l'os spongieux humain : Evaluation du risque fracturaire

Abstract : To prevent bone pathology, the aim of this study is to test a new methodology to evaluate fracture risk of human calcaneus cancellous bone. By using i) clinical data (bone mineral density, microstructure, DXA, Scanner X, Histomorphometry) and ii) high definition imaging techniques (RMN at 78 µm and µComputed Tomography at 10µm), it will be possible to estimate cancellous bone mechanical properties (Young Modulus and compressive maximal stress). Two tests have been implemented : a compressive test on a cubic sample of cancellous bone, and secondly, a bending test on trabecular bone. Different finite element models of these have been used and allow to determine mechanical properties of trabecular bone. Fracture risk can be evaluated by damage quantification and tissue strain level. Results of this methodology will then be compared with those obtained by classical clinical techniques.
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https://tel.archives-ouvertes.fr/tel-00003145
Contributor : Helene Follet <>
Submitted on : Monday, July 21, 2003 - 10:34:58 PM
Last modification on : Tuesday, November 24, 2020 - 4:30:06 PM
Long-term archiving on: : Friday, April 2, 2010 - 6:58:24 PM

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  • HAL Id : tel-00003145, version 1

Citation

Hélène Follet. Caractérisation Biomécanique et Modélisation 3D par Imagerie X et IRM haute résolution de l'os spongieux humain : Evaluation du risque fracturaire. Sciences du Vivant [q-bio]. INSA de Lyon, 2002. Français. ⟨tel-00003145⟩

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